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st_swithin
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10069
Nov 2002
time: 05:31
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OH GOD NO!! SAY IT ISN'T SO!! Maybe I really AM dying. Screw this health crap, I'm getting some more coffee.
http://www.canoe.ca/Health9905/26_insomnia.html
Researchers discover new form of fatal insomnia
By KATHARINE WEBSTER -- The Associated Press
Canada Health Profile
Researchers have discovered a brain-wasting disease that begins with severe insomnia and ends in hallucinations and death.
The disease, sporadic fatal insomnia, is caused by the same type of deformed proteins, known as prions, that cause mad cow disease and its human variant, Creutzfeldt-Jakob disease, according to two studies.
There is no known treatment or cure. It is not clear what causes the disease, but scientists know it is not inherited. And unlike one type of Creutzfeldt-Jakob disease, it is not believed to come from infected meat.
Instead, scientists suspect it is caused by a spontaneous mutation in a single brain or nerve cell.
So far, they have identified only six cases of the disease, but there could be others that were misdiagnosed as other mind-destroying illnesses such as Alzheimer's disease.
Prions are proteins with Jekyll-and-Hyde personalities that cluster in the brain. When their molecules are folded into the correct shape, prions are benign, though no one knows their function.
Folded the wrong way, prions induce other proteins to mimic them. The misfolded prions then accumulate in parts of the brain, causing the tissue to break down and become full of holes, like a sponge.
Different prion diseases attack different parts of the brain, causing characteristic types of dementia and death.
Some are infectious, like mad cow disease in cattle and scrapie in sheep and goats. In humans, prion diseases are either inherited, caught from eating contaminated meat, or spontaneous.
Researchers have previously identified an inherited prion disorder whose main symptom is sleeplessness, called fatal familial insomnia.
In a case outlined in Thursday's New England Journal of Medicine, a 44-year-old patient had all the symptoms of the inherited disease, including prions with the same "signature," but without the inherited mutation. The case was reported by Dr. James Mastrianni, a neurologist at the University of Chicago.
The spontaneous, or sporadic, versions of the prion diseases are rare, but more common than their inherited counterparts.
Prions are still controversial. Some researchers believe it is impossible for proteins to replicate and cause disease, since they do not contain genetic material. These researchers believe the diseases are instead caused by as-yet-undiscovered viruses.
However, the new studies add to evidence the infection is caused by the abnormal shape of the prions, not another agent, Drs. Pierluigi Gambetti and Piero Parchi of Case Western Reserve University said in an accompanying editorial.
Gambetti and Parchi have described five similar cases of non-inherited fatal insomnia in a study scheduled to appear in the journal Neurology.
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Static Universe
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This disease is bull****. When will scientists finally admit that the deaths are caused by Freddy Krueger?
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st_swithin
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10069
Nov 2002
time: 05:31
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Dude, that's not funny. I already have trouble sleeping without worrying that Robert Englund wearing latex and hedge trimmer gloves is going to visit me at night.
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st_swithin
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10069
Nov 2002
time: 05:31
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I thought Jason and Freddie already duked it out. I don't know who won, though.
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st_swithin
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10069
Nov 2002
time: 05:31
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moose.
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All times are GMT. The time now is 05:31.
Apolyton Time is 00:31. |
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18-10-2003 11:33
Come back here! I'll bite your knees off!
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