08-10-2002 00:20									#31
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I'm impressed by all the wart-bearers we have.

If you ever have a petting session with a blind person you may find they can read you like a book.

	08-10-2002 00:22									#32
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Well it is kind of coincidental that this thread full of warthogs comes up on while I have had warts unexpectedly springing up all weekend seemingly from nowhere...

	08-10-2002 00:23									#33
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Been to France recently?

	08-10-2002 00:25									#34
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I have a cough.

	08-10-2002 00:29									#35
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quote: Originally posted by Provost Harrison They are warts as they are on the soft parts of my hands in little points, they have just shot up over the weekend. They aren't serious but unsightly. I wonder if I have shaken hands with someone I shouldn't have done

there is a certain sort of wort which shows desease

yours sounds unusual, so I would reccomend getting it looked at

Jon Miller

	08-10-2002 00:31									#36
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umm

Jon Miller

	08-10-2002 00:34									#37
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I have weak knees that are probably going to completely give out one day soon.
I have a hip that tends to dislocate itself every once in a while.
My hearing is crap.

Other than that, I feel great!

	08-10-2002 00:34									#38
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Yes, I have had a really draining flu whilst trying to work a full week which absolutely killed me. I am OK now, but I was dead on my feet last week. I think my immune system has been a bit run down lately

	08-10-2002 00:41									#39
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Current chronic problems:

Blackheads. My nose pumps out more oil than Kuwait.

Shortsighted.

Allergic to concentrated lemon drink and bright lights. Yes, lemon drink. That artificial stuff in proletarian supermarkets. Real lemon juice is fine.

Ralph Wiggum-esque bleeding noses. Daily.

Vanished chronic problems:

Asthma. Gone since I moved out of my parents home.

Eczema. Gone for ages.

Warts, 10+ on each hand. Don't take any crap from the doctor about using chemicals or liquid nitrogen to burn them off, what you need is local anasthetic and a surgical tool. He ripped the three biggest ones off and it sparked an immune response which eliminated all the others.

	08-10-2002 00:43									#40
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my hearing is bad

and I need glasses but do not wear them

and I have asthma and allergies (pretty bad)

Jon Miller

	08-10-2002 00:47									#41
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Well I am using a bit of glutaraldehyde to keep them under control at the moment, it worked like a treat on my verrucas and the last time I had warts

Ah yes, I have (near as damn it) perfect eyesight. I think I would be lost without it (if you pardon the pun )

And I seem to have shocking teeth. Every time I go to the dentist I need a new filling or three, although I brush my teeth religiously (no, not with a crucifix )

	08-10-2002 00:48									#42
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You know what? When I think about how bad life is and want to end it, I'll just think 'At least I'm not chegitz'

	08-10-2002 00:56									#43
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I'm physically okay, I should sport more but everything works fine.

	08-10-2002 01:36									#44
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I forgot to mention I have tinnitus. I also have Seasonal Affactive Disorder, like RJ mentions. However, now that I'm in Florida, this constant sun has me in a blissful state, when I'm actually out in it).

On the flip side, I used to have incredible sight. I am rather annoyed that I am now down to 20/20 vision. I have a very strong sense of smell, which is both a bane and boon.

RJ, what I mean by an allergy to extreme cold is that I break out in hives when exposed to cold. I first noticed it in highschool while practicing American football. And me living in frigid Chicago for the next 20 years.

	08-10-2002 03:41									#45
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Let's see:
-evil mutant bolivian athelete's foot that's been on the sole and part of the heel of my foot for nearly ten years now.
-nearsighted
-mild hypoglysemia (the opposite of diabetes).
-minor heart murmur.
-chipped tooth (goddam beer bottle )
-chronic stiff neck
-chronic sinus headaches
-really bad sense of smell
-I get ear infections at least once a year

	08-10-2002 03:50									#46
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I have allergies to just about everything (some cats, lots of pollin, most fish, lots of miscellaneous chemicals - including tobacco smoke, etc.).
I have asthma (although it's been a couple years since I've had an attack).
I'm out of shape (but I've been working on that the past couple weeks).

	08-10-2002 04:00									#47
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Mentally:

	08-10-2002 04:09									#48
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near-sightedness

unexplainable nose bleeding

sleepwalking

semi-alcoholism

dandruff

cold fingers

	08-10-2002 04:10									#49
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quote: Originally posted by chegitz guevara RJ, what I mean by an allergy to extreme cold is that I break out in hives when exposed to cold. And me living in frigid Chicago for the next 20 years.

Strange.

	08-10-2002 04:25									#50
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Lets see

mild asthma
near-sighted
alpha thalassemia ( assymptomatic but interesting)
Translocation of the 4 and 10 chromosomes ( no symptoms known but the medical types really have no idea what effects it may have)

edit -spelling

	08-10-2002 04:36									#51
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Chromosomal mutations? Interesting. So 4 and 10 translocation is harmless? There are some which are harmful. It is believed that it effects patterns of transcription in chromosomal material. Genes 'switch' on and off depending on point in the cell cycle, type of cell, stage in development, etc, etc. Now genes occur in blocks and are switched on and off in bulk, and there will only be one site for the initiation of transcription. Now if there is a translocation with the origin of translocation in the middle of one of those regions, you could end up moving a block of genes to a region where it will be transcribed in a different pattern as it will be dependent on a different set of transcriptional factors and promotors, and the same will happen to the other set of genes.

Hence you will be transcribing and translating proteins that have could have a dramatic effect on the cell when they shouldn't be active at that point, and not transcribing others when they are needed.

I really need to draw a diagram for this

...so is though

	08-10-2002 04:47									#52
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Provost

so far they have identified something like 6 people in our family with what they call "balanced" translocation of 4 and 10-- I have the documents somewhere that indicated the break points.

They call it balanced as there seems to be no genetic material missing, simply some material has switched places. We have been seeing geneticists to determine the impacts and so far they just don't know although they say we are at increased chance for various birth defects -- (although the amount of material that is switched is so great that they believe any child of mine that had an "unbalanced" situation, would not survive implantation let alone be viable to be carried to term. ) Also of the 6 identified carriers, only 2 were women and neither of them has successfully carried a pregnancy to term. All 4 men have fathered children and it appears to be about 50/50 whether such children have " normal" chromosomes or carry the translocation.

	08-10-2002 04:54									#53
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Yes, the genome is a very complicated thing. We may know it's sequence, and what gene does what. But that's the basics of the genome. It's not a linear storage system, unlike a hard drive. It's an active system, changing through methylation, transcription factors binding depending on signals within the cell and dependent on cell cycle.

The problem is, you can't understand the complexity of the genome and it's patterns of transcription and how it changes without understanding the functioning of the entire organism, and vice versa.

The genome project is the tip of the iceberg, there is so much to understand about the 'mechanics' of the genome. How this break affects an organism is unknown, because even the slight alteration of one gene, or the points at which it is expressed has a vast effect. It is like changing a cog inside a clock...the effect could be dramatic on the large scale...

	08-10-2002 04:56									#54
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Back pain
Underweight

Not too bad I guess.

	08-10-2002 04:59									#55
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Hey, a compromise Skanky, you have some of my weight and we'd both balance out at normal

	08-10-2002 05:24									#56
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Blind as a bat

(seriously, thanks to astigmatism the widest part of my glasses is about as thick as 2x2p coins). Still too stubborn to wear glasses though!

Almost completely deaf in my right ear.

10 years ago my (ex)girlfriend fired a rifle next to my head on a shooting range; before I'd put my mufflers on, stupid *****. Burst eardrum and remained so infected and weak I find it hard to hear on that side, dammit.

Back injury.

One of my old (menial, predegree)jobs had me working behind a till at a petrol station, as well as putting together newspapers, which meant running backwards and forwards with heavy bundles of newspaper suppliments, usually taller than me, trying to back to the till asap to serve ugly scotsmen. Needless to say I put my back out, and it still gives me gyp when I do heavy lifting.


Appart from that lot (and acid flashbacks) I'm in a rude state of health, at 29!

Provost, once had a wart on the inside of my nose! How the hell it got there, God only knows...

	08-10-2002 05:29									#57
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If only it were that simple.

	08-10-2002 05:30									#58
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I dunno, a hosepipe, a vaccum, few incisions. Bobs yer uncle.

	08-10-2002 05:35									#59
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Good god, I must get my jabs before the next Poly meet...

	08-10-2002 11:18									#60
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acne..bad bad bad bad......*shudders*
asthma....though it had faded away for the most part
depression/bipolardisorder/borderline personality disorder...i'm a nut!
slightly hard of hearing
migraines
chest pains associated with stress